Opportunity Information: Apply for RFA AA 24 007
The Specialized Alcohol Research Centers (P50 Clinical Trial Optional) opportunity, RFA-AA-24-007, is a National Institutes of Health (NIH) funding announcement from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) that supports the creation or continuation of specialized, interdisciplinary alcohol research centers using the P50 center grant mechanism. The central goal of the program is to provide scientific leadership and to accelerate collaborative, team-based research that addresses major questions aligned with NIAAA's mission. In practice, these centers are expected to function as organized hubs that bring together investigators, disciplines, and shared resources to pursue coordinated, goal-directed research programs that would be difficult to execute through individual projects alone.
The research scope is broad and spans biomedical, behavioral, and population-focused topics related to alcohol use and its consequences. The NOFO highlights priority areas that include understanding the nature and causes of alcohol use disorder (AUD), the etiology and genetics of alcohol-related conditions, improvements in diagnosis, and the development and testing of treatment and prevention approaches. It also explicitly emphasizes alcohol-related end-organ diseases and the downstream biomedical, psychosocial, and economic impacts of alcohol across the lifespan. A notable focus is the inclusion of research that addresses differences and inequities across racial and ethnic groups and other health disparity populations, signaling that applications that meaningfully incorporate health disparities considerations, inclusive cohorts, and equitable research approaches are strongly aligned with the program's intent.
Beyond producing research findings, these centers are also expected to serve as regional or national resources. That role can include providing infrastructure, expertise, and shared services that strengthen alcohol research capacity more broadly, as well as contributing to the development of new methods, technologies, and innovative approaches that enable sustained progress in the field. In other words, NIAAA is not only funding sets of studies; it is investing in durable, collaborative research ecosystems that can generate new tools, train or support investigators indirectly through shared resources, and push the science forward through coordinated leadership.
The funding instrument is a discretionary grant under the health activity category, associated with CFDA number 93.273. The notice specifies that clinical trials are optional, meaning applicants may propose projects that include clinical trials if scientifically appropriate, but they are not required to do so. The listed award ceiling is $1,150,000, and the original application closing date is November 15, 2024. The opportunity was created on May 7, 2024.
Eligibility is broad and includes many types of U.S.-based organizations and government entities. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; and Native American tribal organizations that are not federally recognized. It also includes public housing authorities/Indian housing authorities, nonprofits with or without 501(c)(3) status (other than institutions of higher education), for-profit organizations other than small businesses, and small businesses. The NOFO also calls out several categories of "other eligible applicants," including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.
At the same time, there are clear restrictions related to non-U.S. entities. Non-domestic (non-U.S.) organizations are not eligible to apply as applicant institutions, and non-domestic components of U.S. organizations are also not eligible. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed, which typically means a U.S. applicant can include certain well-justified international elements or collaborations as part of the project structure, provided they meet NIH policy requirements and the application remains led by an eligible domestic applicant organization.
Overall, this NOFO is designed for applicants capable of assembling a cohesive center with multiple coordinated activities that collectively advance alcohol research. Competitive applications are likely to reflect strong interdisciplinary collaboration, a clear and compelling center-wide scientific vision, and a plan to function as a resource that advances methods, technology, and approaches for the broader alcohol research community, while also addressing AUD and alcohol-related health outcomes in diverse populations, including health disparity groups, across the lifespan.Apply for RFA AA 24 007
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Specialized Alcohol Research Centers (P50 Clinical trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
- This funding opportunity was created on 2024-05-07.
- Applicants must submit their applications by 2024-11-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,150,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
FAQs: Specialized Alcohol Research Centers (P50 Clinical Trial Optional) - RFA-AA-24-007
What is the Specialized Alcohol Research Centers (P50 Clinical Trial Optional) funding opportunity?
RFA-AA-24-007 is a National Institutes of Health (NIH) funding announcement from the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It supports the creation or continuation of specialized, interdisciplinary alcohol research centers using the P50 center grant mechanism.
What is the main goal of this program?
The central goal is to provide scientific leadership and accelerate collaborative, team-based research that addresses major questions aligned with NIAAA's mission. These centers are intended to operate as organized hubs that coordinate investigators, disciplines, and shared resources to pursue goal-directed research that is difficult to execute through individual projects alone.
What is the P50 center grant mechanism intended to support here?
The P50 mechanism is used to support integrated, coordinated research programs with multiple linked activities, shared resources, and interdisciplinary collaboration. Under this opportunity, the expectation is a cohesive center-wide scientific vision that drives a coordinated set of research efforts.
What kinds of research topics are within scope?
The scope is broad and includes biomedical, behavioral, and population-focused research related to alcohol use and its consequences. The announcement highlights priorities such as alcohol use disorder (AUD), the etiology and genetics of alcohol-related conditions, improvements in diagnosis, and the development and testing of treatment and prevention approaches.
Does the NOFO emphasize alcohol-related diseases beyond AUD?
Yes. It explicitly emphasizes alcohol-related end-organ diseases and the downstream biomedical, psychosocial, and economic impacts of alcohol across the lifespan.
Are health disparities and equity-related research encouraged?
Yes. The opportunity notably emphasizes research that addresses differences and inequities across racial and ethnic groups and other health disparity populations. Applications that meaningfully incorporate health disparities considerations, inclusive cohorts, and equitable research approaches are strongly aligned with the program's intent.
Are clinical trials required?
No. Clinical trials are optional. Applicants may propose projects that include clinical trials if scientifically appropriate, but clinical trials are not required.
What does "clinical trial optional" mean in practice?
It means your proposed center can include clinical trial activities, but it does not have to. The center can be entirely non-clinical-trial research, or it can combine clinical trial and non-clinical-trial components, depending on what best fits the scientific aims.
What else are these centers expected to do besides produce research findings?
Beyond generating research results, centers are expected to serve as regional or national resources. This can include providing infrastructure, expertise, and shared services that strengthen alcohol research capacity, as well as developing new methods, technologies, and innovative approaches that enable sustained progress in the field.
How does the NOFO describe the role of shared resources and coordination?
The centers are expected to function as organized hubs that bring together investigators, disciplines, and shared resources to pursue coordinated, goal-directed research programs that would be difficult to carry out through individual projects alone.
What is the maximum award amount listed for this opportunity?
The listed award ceiling is $1,150,000.
When is the application due?
The original application closing date is November 15, 2024.
When was this opportunity created?
The opportunity was created on May 7, 2024.
Which NIH institute is sponsoring this opportunity?
The sponsoring institute is the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the NIH.
What is the CFDA number associated with this program?
The opportunity is associated with CFDA number 93.273.
What type of funding instrument is this?
It is a discretionary grant under the health activity category, using the P50 center grant mechanism.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S.-based organizations and government entities, including state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; and Native American tribal organizations that are not federally recognized.
Are nonprofit organizations eligible?
Yes. Nonprofits with or without 501(c)(3) status (other than institutions of higher education) are eligible.
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are eligible, and small businesses are also eligible.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are listed among "other eligible applicants."
Are minority-serving institutions specifically identified as eligible?
Yes. The NOFO calls out several categories, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other similar entities listed as "other eligible applicants."
Are eligible federal agencies allowed to apply?
Yes. Eligible federal agencies are included among the "other eligible applicants" listed in the announcement.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly listed among the "other eligible applicants."
Can a non-U.S. (non-domestic) organization apply as the applicant institution?
No. Non-domestic (non-U.S.) organizations are not eligible to apply as applicant institutions under this opportunity.
Can a U.S. organization apply if the work is led by a non-U.S. component of that organization?
No. Non-domestic components of U.S. organizations are also not eligible.
Are any international elements allowed at all?
Yes. Foreign components (as defined in the NIH Grants Policy Statement) are allowed. This generally means an eligible U.S. applicant may include well-justified international elements or collaborations as part of the overall project structure, consistent with NIH policy, while the application remains led by an eligible domestic applicant organization.
What kinds of applications are likely to be competitive based on the description provided?
Competitive applications are likely to show strong interdisciplinary collaboration, a clear and compelling center-wide scientific vision, and a credible plan to function as a resource that advances methods, technology, and approaches for the broader alcohol research community. The description also indicates strong alignment for centers that address AUD and alcohol-related health outcomes in diverse populations, including health disparity groups, across the lifespan.
Is this opportunity intended for single-project proposals or multi-component center programs?
It is intended for cohesive center programs with multiple coordinated activities, shared resources, and organized collaboration, rather than stand-alone individual research projects.
Browse more opportunities from the same category: Health
Next opportunity: USDA Forest Service - GLRI Forest Restoration 2024
Previous opportunity: Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA AA 24 007
Applicants also applied for:
Applicants who have applied for this opportunity (RFA AA 24 007) also looked into and applied for these:
| Funding Opportunity |
|---|
| Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01 Independent Clinical Trial Not Allowed) Apply for RFA HL 25 009 Funding Number: RFA HL 25 009 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01 Independent Clinical Trial Required) Apply for RFA HL 25 008 Funding Number: RFA HL 25 008 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Request for Information for USAID/Namibia Key Populations - Resilience, Innovation, Sustainability, and Empowerment (KP-RISE) Apply for RFI 673 24 Funding Number: RFI 673 24 Agency: South Africa USAID-Pretoria Category: Health Funding Amount: Case Dependent |
| ML/AI Tools to Advance Genomic Translational Research (MAGen) - Coordinating Center (UG3/UH3, Clinical Trials Not Allowed) Apply for RFA HG 24 005 Funding Number: RFA HG 24 005 Agency: National Institutes of Health Category: Health Funding Amount: $800,000 |
| ML/AI Tools to Advance Genomic Translational Research (MAGen) - Development Sites (UG3/UH3 Clinical Trials Not Allowed) Apply for RFA HG 24 004 Funding Number: RFA HG 24 004 Agency: National Institutes of Health Category: Health Funding Amount: $1,600,000 |
| NINDS Research Education Opportunities (R25 Clinical Trial Not Allowed) Apply for PAR 24 200 Funding Number: PAR 24 200 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Access and Manipulation of Brain Cell Subtypes Implicated in Aging and AD/ADRD (R61/R33 Clinical Trial Not allowed) Apply for RFA AG 25 024 Funding Number: RFA AG 25 024 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NEI Research for Low Vision and Blindness Accessibility Tools (R61/R33 Clinical Trial Optional) Apply for RFA EY 24 003 Funding Number: RFA EY 24 003 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIDCR Dual Degree Dentist Scientist Predoctoral to Postdoctoral Transition Award (F99/K00 Independent Clinical Trial Not Allowed) Apply for PAR 25 021 Funding Number: PAR 25 021 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Safety and Efficacy of Amyloid-Beta Directed Antibody Therapy in Mild Cognitive Impairment and Dementia with Evidence of Lewy Body Dementia and Amyloid-Beta Pathology (U01 - Clinical Trial Required) Apply for RFA NS 25 010 Funding Number: RFA NS 25 010 Agency: National Institutes of Health Category: Health Funding Amount: $6,700,000 |
| Single Source: NINDS Exploratory Clinical Trials (U01 Clinical Trial Required) Apply for PAR 24 215 Funding Number: PAR 24 215 Agency: National Institutes of Health Category: Health Funding Amount: $2,000,000 |
| NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) Apply for PAR 24 208 Funding Number: PAR 24 208 Agency: National Institutes of Health Category: Health Funding Amount: $250,000 |
| Service Area Competition Apply for HRSA 25 013 Funding Number: HRSA 25 013 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Early-Stage Dissemination and Implementation Research in Communication Disorders (R21 Clinical Trial Optional) Apply for RFA DC 24 008 Funding Number: RFA DC 24 008 Agency: National Institutes of Health Category: Health Funding Amount: $275,000 |
| A System-Level Syndemic Approach to Improve HIV Care and Treatment for People from Racial and Ethnic Minority Groups – Evaluation and Technical Assistance Provider (ETAP) Apply for HRSA 24 108 Funding Number: HRSA 24 108 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| A System-Level Syndemic Approach to Improve HIV Care and Treatment for People from Racial and Ethnic Minority Groups – Demonstration Systems Apply for HRSA 24 107 Funding Number: HRSA 24 107 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Appalachian Region Healthcare Support Program Apply for HRSA 24 119 Funding Number: HRSA 24 119 Agency: Health Resources and Services Administration Category: Health Funding Amount: $1,500,000 |
| HIV Clinical Training Tracks in Primary Care Residency Programs (HTR Program) Apply for HRSA 24 109 Funding Number: HRSA 24 109 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Technology-enabled Collaborative Learning Program Apply for HRSA 24 121 Funding Number: HRSA 24 121 Agency: Health Resources and Services Administration Category: Health Funding Amount: $475,000 |
| Delta Region Maternal Care Coordination Program Apply for HRSA 24 120 Funding Number: HRSA 24 120 Agency: Health Resources and Services Administration Category: Health Funding Amount: $450,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA AA 24 007", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.