Opportunity Information: Apply for 23 569
This grant opportunity, titled "A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise" (Funding Opportunity Number 23-569), is a joint effort between the National Science Foundation (NSF) and the National Institutes of Health (NIH) to fund research that takes a rigorous, evidence-based look at how the U.S. biomedical research system works and how it might be improved. The central idea is to bring the tools, theories, and methods of the science of science policy community to questions about the biomedical research enterprise, including how research is produced, communicated, evaluated, supported, and translated into impact. Rather than funding biomedical experiments directly, the program is focused on studying the structures and dynamics that shape biomedical research outcomes and the workforce behind them.
On the NSF side, the effort is rooted in the Social, Behavioral and Economic Sciences (SBE) Directorate, which supports basic research about people, organizations, and society, including how social and institutional forces influence behavior and decision-making over the life course. Within SBE, the Science of Science Discovery, Communication and Impact (SoSDCI) program specifically supports research that strengthens the scientific foundation for science and innovation policy. On the NIH side, the participating institute is the National Institute of General Medical Sciences (NIGMS), which is known for supporting fundamental biomedical research that builds core knowledge about biological processes and helps enable future advances in diagnosing, treating, and preventing disease. By partnering, SBE and NIGMS aim to build a shared portfolio of studies that can generate actionable insights about the biomedical research system while also advancing generalizable science-of-science knowledge.
A major goal of the solicitation is to encourage projects that can meaningfully analyze key features of the biomedical research enterprise and inform efforts to make it more diverse, innovative, productive, and efficient. That emphasis on the enterprise means proposals could examine topics such as how funding mechanisms influence research directions, how collaboration networks form and affect discovery, how peer review and evaluation practices shape scientific incentives, how scientific communication and dissemination affect uptake and reuse, and how training and career pathways influence who enters, stays, and advances in biomedical research. The program also signals a workforce priority: generating evidence that helps foster a strong and inclusive biomedical workforce and supports the development of future scientific leaders. The intent is not only to describe problems but to develop insights that can guide improvements in how research is organized and supported.
The opportunity is offered as a discretionary grant competition led by NSF, with a funding activity category of science and technology and other research and development. It lists CFDA numbers 47.075 and 93.859, reflecting the NSF and NIH partnership. Eligibility is described as unrestricted, meaning proposals can come from any applicant type, subject to any additional eligibility clarifications in the full solicitation. The award ceiling is $250,000 per award, with an expected 8 awards. The opportunity was created on March 21, 2023, and the original closing date was September 11, 2023.
A practical feature of the solicitation is the strong encouragement for prospective applicants to talk with program officers before submitting. Because this is a coordinated NSF-NIH partnership, that early contact is meant to help investigators confirm that a proposed project fits the priorities and scope of both SBE/SoSDCI and NIGMS, and to reduce the risk of submitting work that is scientifically strong but misaligned with the partnership's goals. In effect, the program is designed to generate high-quality, policy-relevant, methodologically rigorous research that improves understanding of the biomedical research ecosystem and supports better decision-making about how the enterprise is funded, managed, and sustained.Apply for 23 569
- The National Science Foundation in the science and technology and other research and development sector is offering a public funding opportunity titled "A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 47.075, 93.859.
- This funding opportunity was created on Mar 21, 2023.
- Applicants must submit their applications by Sep 11, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQ)
What is the title and funding opportunity number for this grant?
The opportunity is titled "A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise" and it is listed as Funding Opportunity Number 23-569.
Which agencies are partnering on this opportunity?
This is a joint effort between the National Science Foundation (NSF) and the National Institutes of Health (NIH). The NSF side is anchored in the Social, Behavioral and Economic Sciences (SBE) Directorate through the Science of Science Discovery, Communication and Impact (SoSDCI) program, and the NIH partner is the National Institute of General Medical Sciences (NIGMS).
What is the main purpose of the program?
The program funds rigorous, evidence-based research that examines how the U.S. biomedical research enterprise functions and how it could be improved. The emphasis is on studying the structures and dynamics that shape biomedical research outcomes and the workforce behind them, rather than conducting biomedical experiments directly.
What does "science of science" mean in the context of this solicitation?
In this solicitation, "science of science" refers to using tools, theories, and methods commonly used in science-of-science policy research to analyze how research is produced, communicated, evaluated, supported, and translated into impact within the biomedical research system.
Is this funding meant to support biomedical lab experiments or clinical studies?
No. The focus is not on funding biomedical experiments directly. Instead, the program supports research about the biomedical research enterprise itself (for example, how incentives, evaluation, communication, funding, and workforce structures influence biomedical research outcomes).
What NSF program is involved, and what does it typically support?
On the NSF side, this opportunity is rooted in the SBE Directorate, specifically the SoSDCI program. SoSDCI supports research that strengthens the scientific foundation for science and innovation policy, including work that improves understanding of how science is discovered, communicated, and translated into impact.
What NIH institute is participating, and what is it known for?
The participating NIH institute is NIGMS (National Institute of General Medical Sciences). NIGMS is known for supporting fundamental biomedical research that builds core knowledge about biological processes and helps enable future advances in diagnosing, treating, and preventing disease.
What kinds of topics or questions does the solicitation suggest are a good fit?
The solicitation highlights enterprise-level questions, such as how funding mechanisms influence research directions, how collaboration networks form and affect discovery, how peer review and evaluation shape scientific incentives, how communication and dissemination affect uptake and reuse, and how training and career pathways influence entry, retention, and advancement in biomedical research.
What outcomes or impacts is the program trying to encourage?
The program aims to support studies that generate actionable insights to help make the biomedical research enterprise more diverse, innovative, productive, and efficient, while also advancing generalizable science-of-science knowledge that can inform science and innovation policy.
Does the opportunity have a workforce focus?
Yes. The solicitation signals a workforce priority: generating evidence that helps foster a strong and inclusive biomedical workforce and supports the development of future scientific leaders.
What is meant by analyzing "the biomedical research enterprise"?
It means studying the ecosystem that shapes biomedical research, including the systems and practices that influence what research gets done and how it is evaluated, communicated, supported, and translated into impact, as well as how the workforce is trained and sustained.
Is the program interested only in describing problems, or also in informing improvements?
The intent goes beyond describing problems. The solicitation emphasizes developing evidence and insights that can guide improvements in how biomedical research is organized, evaluated, funded, and supported.
What type of funding mechanism is this?
It is offered as a discretionary grant competition led by NSF, with a funding activity category described as science and technology and other research and development.
What are the CFDA numbers associated with this opportunity?
The opportunity lists CFDA numbers 47.075 and 93.859, reflecting the NSF and NIH partnership.
Who is eligible to apply?
Eligibility is described as unrestricted, meaning proposals can come from any applicant type, subject to any additional eligibility clarifications in the full solicitation.
What is the maximum award amount (award ceiling)?
The award ceiling is $250,000 per award.
How many awards are expected?
The opportunity indicates an expectation of 8 awards.
When was the opportunity created, and what was the original closing date?
The opportunity was created on March 21, 2023, and the original closing date was September 11, 2023.
Is there an expectation to contact program officers before submitting?
Yes. Prospective applicants are strongly encouraged to speak with program officers before submitting.
Why is early contact with program officers emphasized?
Because the opportunity is a coordinated NSF-NIH partnership, early contact is intended to help investigators confirm that a proposed project fits the priorities and scope of both NSF SBE/SoSDCI and NIH NIGMS, and to reduce the risk of submitting a proposal that is strong scientifically but misaligned with the partnership's goals.
What is the overall emphasis of the portfolio this partnership is trying to build?
SBE and NIGMS aim to build a shared portfolio of studies that generate actionable insights about the biomedical research system and improve decision-making about how the enterprise is funded, managed, and sustained, while also contributing to generalizable science-of-science research.
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